Early Stage Researcher 8

Novel immunoassays for Alzheimer's disease

- Application closed -

The goal of the project is to develop novel immunoassays to improve the diagnosis of Alzheimer’s Disease.

Your main tasks and responsibilities in this project will be:

  • to develop customized panels of immunoassays for analysis of novel biomarker candidates;
  • to optimize these panels for biomarker detection in both CSF and blood using state of the art technologies, such as enzyme-linked immunosorbent assays (ELISA) or single molecule arrays;
  • to technically and clinically validate novel tests in relevant patient samples from different cohorts;
  • to process and to analyse the data;
  • to communicate results by means of oral presentations and scientific publications;
  • to perform one secondment (internship) of n. 6 (six) months at the Quanterix Corporation (US), to apply an ultrasensitive Simoa blood-based assay.

We look for excellent candidates with a M.Sc. degree in Biology, Biotechnology, Biochemistry, Chemistry or related fields.

The Host Institution of the project is: University of Perugia, Italy.

As an early stage researcher you will work in the stimulating environment of the Laboratory of Clinical Neurochemistry, Section of Neurological Clinic - Department of Medicine of the University of Perugia, headed by Prof. Lucilla Parnetti, in collaboration with the postdocs Dr. Silvia Paciotti and Dr. Samuela Cataldi. You will be part of a multidisciplinary team, with experience in the field of biomarker clinical validation.